I do not think native americans were all that different than europeans at their first meeting.
A clan larger than 50 individuals requires social constructs to keep it together - god, money, prestige, nation, etc - intimacy and blood relations no longer sufficient with larger groups. Two strangers would fight side by side for the first time for nation, for god, for money, as examples.
And so Natives invented their gods, had their money, defined prestige and success, had their nations and inevitable wars all as social glue for their societies - all of it human construct - none of it real.
Europeans had advanced technologically - especially in devising new and more deadly ways to kill each other - which served to elevate and pervert their social constructs to psychopathy. Unhappily for the natives they had not yet reached those levels and were systematically destroyed - either by disease or murder.
But I think they would have had they been given the time.